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The history of the medications used in mental disorders has developed a lot through years. The discovery of modern drugs prevailed during the 20th century. Lithium, a mood stabilizer, was discovered as a treatment of mania, by John F. Cade in 1949, "and Hammond (1871) used lithium bromide for 'acute mania with depression'". [14]
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
The second leading cause of global disability burden in 2020 was unipolar depression, and research showed that depression was twice as likely to be prevalent in women than in men. [ 9 ] [ 10 ] [ 13 ] Gender-based mental health disparities suggest that gender is a factor that could be leading to unequal health outcomes.
Men are less likely to seek help. Gender can also be a predictor of whether patients choose to seek help. In 2022, 2.3 million male patients received mental health treatment versus 2.8 million women.
Several treatment guidelines recommend pharmaceutical treatments that include either the combination of a second-generation antidepressant and atypical antipsychotic or tricyclic antidepressant monotherapy or electroconvulsive therapy (ECT) as the first-line treatment for unipolar psychotic depression. [13] [14] [15] [16]
Although the use of antidepressants has been widely used, not all agree that it is an appropriate treatment for some minor depression disorder settings. [8] Another alternative that has been researched is the use of St. John's wort (Hypericum perforatum). This herbal treatment has been studied by various groups with various results. [9]
These treatments can include cognitive behavioral therapy, acceptance and commitment therapy, or forms commonly used for chronic pain treatments. Interventional techniques can also be used. [ 9 ] Treatments can address underlying feelings and emotional conflicts that can lead to psychogenic pain, as well as other potential causes of dysfunction ...
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
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