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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Contrave. Contrave is yet another oral weight loss medication. ... This results in a calorie deficit, which can promote weight loss. ... This is compared to 6.2 pounds after six months of taking a ...
Bupropion, when used for treating long-term weight gain over six to twelve months, results in an average weight loss of 2.7 kilograms (6.0 lb) over placebo. [74] This is not much different from the weight loss produced by several other weight-loss medications such as sibutramine or orlistat . [ 74 ]
0.9 kilograms (2.0 lb) per month more than placebo [75] Amphetamine salts: Obetrol: Approved 1960, withdrawn 1973; Adderall was later approved for ADHD and narcolepsy and is still used for those purposes Phenylpropanolamine: Was an over-the-counter medication ingredient Withdrawn in 2005 due to risk of hemorragic stroke: 1.5 kilograms (3.3 lb) [76]
STEP 1, 3, 4 and 8 trials looked at participants with overweight and obesity without type 2 diabetes. These studies found an average weight loss ranging from almost 15 percent to upwards of 17 ...
Contrave: This medication combines bupropion (an antidepressant) and naltrexone (a drug to treat alcohol and opioid dependence) to help control appetite and cravings while increasing metabolism.
The company has a single product, Contrave, approved for use in the United States in 2014. [ 2 ] [ 3 ] Contrave was designed not only to curb hunger but also reduce cravings. [ 3 ] Observation of the market performance of Qsymia and Belviq suggest overall low demand for pharmaceutical obesity therapies, calling into question earnings potential ...
The FDA in 2014 approved Contrave tablets as a weight loss treatment featuring naltrexone (an opioid antagonist) and bupropion (an antidepressant) as active ingredients. Carolina Rudah/istockphoto ...