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A midlife crisis is a transition of identity and self-confidence that can occur in middle-aged individuals, typically 45 to 64/65 years old. [1] [2] [3] The phenomenon is described as a psychological crisis brought about by events that highlight a person's growing age, inevitable mortality, and possible lack of accomplishments in life.
A stressor is a chemical or biological agent, environmental condition, external stimulus or an event seen as causing stress to an organism. [1] Psychologically speaking, a stressor can be events or environments that individuals might consider demanding, challenging, and/or threatening individual safety.
Abiotic stressors are any ecological, geological, or climate changes that causes stress to the animal, such as increased temperatures and natural disasters. [13] Biotic stressors are living things related complications that causes stress, such as dominance, pollution, infection, social pressures, and competition.
Definitions differ, and may be along the lines of continual activation of the stress response, [43] stress that causes an allostatic shift in bodily functions, [5] or just as "prolonged stress". [44] For example, results of one study demonstrated that individuals who reported relationship conflict lasting one month or longer have a greater risk ...
Prolonged stress can disturb the immune, digestive, cardiovascular, sleep, and reproductive systems. [17] For example, it was found that: Chronic stress reduces resistance of infection and inflammation, and might even cause the immune system to attack itself. [27] Stress responses can cause atrophy of muscles and increases in blood pressure. [28]
Various symptoms are associated with mid-life crises, such as stress, boredom, self-doubt, compulsivity, changes in the libido and sexual preferences, rumination, and insecurity. [48] [50] [51] In public discourse, the mid-life crisis is primarily associated with men, often in direct relation to their career. But it affects women just as well.
For example, in the context of depression, the diathesis-stress model can help explain why Person A may become depressed while Person B does not, even when exposed to the same stressors. [7] More recently, the diathesis-stress model has been used to explain why some individuals are more at risk for developing a disorder than others. [9]
These changes can lead to transgenerational stress inheritance. [1] Epigenetic modifications play a role in the development and heritability of these disorders and related symptoms. For example, regulation of the hypothalamus-pituitary-adrenal axis by glucocorticoids plays a major role in stress response and is known to be epigenetically regulated.