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  2. Ticagrelor - Wikipedia

    en.wikipedia.org/wiki/Ticagrelor

    In the US, ticagrelor is indicated to reduce the risk of stroke in people with acute ischemic stroke or high-risk transient ischemic attack. [5]In the EU, ticagrelor, co-administered with acetylsalicylic acid (aspirin), is indicated for the prevention of atherothrombotic events in adults with acute coronary syndromes or a history of myocardial infarction and a high risk of developing an ...

  3. Thienopyridine - Wikipedia

    en.wikipedia.org/wiki/Thienopyridine

    Ticagrelor (Brilinta) is often listed with thienopyridine inhibitors and has similar indications for use but is not a thienopyridine. It is a cyclo-pentyltriazolo-pyrimidine that is distinct from the mechanism of the thienopyridines in that it reversibly (rather than irreversibly) inhibits the P2Y 12 receptor.

  4. Bentracimab - Wikipedia

    en.wikipedia.org/wiki/Bentracimab

    Bentracimab is a monoclonal antibody medication which has been shown in phase one and two clinical trials to function as a reversal agent for the anti–blood clotting drug ticagrelor (which acts as a P2Y 12 inhibitor and is sold under the brand name Brilinta among others). [2]

  5. AstraZeneca’s Wins FDA Priority Review For Heart Drug Brilinta

    www.aol.com/news/astrazeneca-wins-fda-priority...

    AstraZeneca Plc (AZN) announced on Thursday that the Food and Drug Administration (FDA) has accepted a supplemental New Drug Application (sNDA) and granted a priority review for its heart ...

  6. FDA Is Set Decide the Fate of AstraZeneca's Heart Drug Brilinta

    www.aol.com/news/2010-12-15-fda-astrazeneca...

    More than a year after AstraZeneca (AZN) filed for approval of its potential blockbuster heart drug Brilinta, the Food and Drug Administration appears ready to make its decision on Thursday. The ...

  7. Vortioxetine - Wikipedia

    en.wikipedia.org/wiki/Vortioxetine

    Vortioxetine was previously sold under the brand name Brintellix in the United States, but in May 2016, the US Food and Drug Administration (FDA) approved a name change to Trintellix in order to avoid confusion with the blood-thinning medication Brilinta . [57] [58] Other brand names include Torvox, Vantaxa, Voxigain, and Trivoxetin.

  8. Antiplatelet drug - Wikipedia

    en.wikipedia.org/wiki/Antiplatelet_drug

    Patients who require the use of antiplatelet drugs are: stroke with or without atrial fibrillation, any heart surgery (especially prosthetic replacement heart valve), Coronary Heart Disease such as stable angina, unstable angina and heart attack, patients with coronary stent, Peripheral Vascular Disease/Peripheral Arterial Disease and apical ...

  9. Brexpiprazole - Wikipedia

    en.wikipedia.org/wiki/Brexpiprazole

    Brexpiprazole, sold under the brand name Rexulti among others, is an atypical antipsychotic medication used for the treatment of major depressive disorder, schizophrenia, and agitation associated with dementia due to Alzheimer's disease.

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