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  2. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    Although anxiety can temporarily increase as a withdrawal symptom, there is evidence that a reduction or withdrawal from benzodiazepines can lead to a reduction of anxiety symptoms in the long run. [4] [5] Due to these increasing physical and mental symptoms from long-term use of benzodiazepines, slow withdrawal is recommended for long-term users.

  3. Benzodiazepine withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_withdrawal...

    This antagonism can precipitate acute withdrawal symptoms, that can persist for weeks or months before subsiding. The symptoms include depression, anxiety, psychosis, paranoia, severe insomnia, paresthesia, tinnitus, hypersensitivity to light (photophobia) and sound (hyperacusis), tremors, status epilepticus, suicidal thoughts and suicide ...

  4. Lorazepam - Wikipedia

    en.wikipedia.org/wiki/Lorazepam

    Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. [14] It is used to treat anxiety (including anxiety disorders ), trouble sleeping , severe agitation , active seizures including status epilepticus , alcohol withdrawal , and chemotherapy-induced nausea and vomiting . [ 14 ]

  5. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    If symptoms of discontinuation are severe, or do not respond to symptom management, the antidepressant can be reinstated and then withdrawn more cautiously, or by switching to a drug with a longer half life (e.g., fluoxetine), and then tapering and discontinuing that drug. [21] In severe cases, hospitalization may be required. [2]

  6. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Lorazepam has particularly marked amnesic properties that may make it more effective when amnesia is the desired effect. [ 24 ] : 693 Benzodiazepines are well known for their strong muscle-relaxing properties and can be useful in the treatment of muscle spasms, [ 24 ] : 577–578 although tolerance often develops to their muscle relaxant ...

  7. Benzodiazepine dependence - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_dependence

    Reducing the dose or discontinuing benzodiazepines may be indicated in such cases. Withdrawal symptoms can persist for quite some time after discontinuing benzodiazepines. Some common protracted withdrawal symptoms include anxiety, depression, insomnia, and physical symptoms such as gastrointestinal, neurologic, and musculoskeletal effects. The ...

  8. Lorazepam challenge - Wikipedia

    en.wikipedia.org/wiki/Lorazepam_challenge

    The lorazepam challenge is a diagnostic tool used in the clinical diagnosis of catatonia. [1] Upon treatment with lorazepam, other benzodiazepines, or zolpidem, a rapid reversal of the catatonic state is often observed in catatonic patients. A positive response is usually defined as a 50% reduction in catatonic symptoms using a standardized ...

  9. Major depressive episode - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_episode

    The two main symptoms of a major depressive episode are a depressed mood and a loss of interest or pleasure. [3] From the list below, one bold symptom and four other symptoms must be presented for at least 2 weeks for a diagnosis of a major depressive episode. Weight loss or gain; Change in body activity (psychomotor changes) Change in sleep ...

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