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Tetrahydrofuran (THF), or oxolane, is an organic compound with the formula (CH 2) 4 O. The compound is classified as heterocyclic compound , specifically a cyclic ether . It is a colorless, water- miscible organic liquid with low viscosity .
Phase behavior Triple point: 164.76 K (−108.39 °C), ? Pa Critical point: 541 K (268 °C), 5190 kPa Std enthalpy change of fusion, Δ fus H o: 8.540 kJ/mol Std entropy change
For example, tetrahydrofuran-3-one (3-ketotetrahydrofuran) [12] and 3-aminotetrahydrofuran [13] have been synthesized from 3-hydroxytetrahydrofuran and used in pharmaceutical syntheses. Additionally, additive amounts (0.05-0.15 weight %) of the nitrate ester manufactured by sulfuric acid - nitric acid nitration of 3-hydoxytetrahydrofuran have ...
It is dissimilar vs ethers such as tetrahydrofuran. Like enol ethers, 2,5-disubstituted furans are susceptible to hydrolysis to reversibly give 1,4-diketones. Furan serves as a diene in Diels–Alder reactions with electron-deficient dienophiles such as ethyl ( E )-3-nitroacrylate. [ 15 ]
Chemical formula Synonyms CAS number C 10 H 16 N 2 O 8: Ethylenediaminetetraacetic acid (EDTA): 6381–92–6 C 12 H 22 O 11: sucrose: 57–50–1 C 18 H 29 O 3 S: sodium dodecyl benzenesulfonate: 2155–30–0
Deuterated tetrahydrofuran (d 8-THF) is a colourless, organic liquid at standard temperature and pressure. [1] This heterocyclic compound has the chemical formula C 4 D 8 O, and is an isotopologue of tetrahydrofuran. [2] Deuterated THF is used as a solvent in NMR spectroscopy, though its expense can often be prohibitive. [citation needed]
2,2,5,5-tetramethyltetrahydrofuran (TMTHF) or 2,2,5,5-tetramethyloxolane (TMO) is a heterocyclic compound with the formula C 8 H 16 O, or (CH 3) 2 (C(CH 2) 2 OC)(CH 3) 2.It can be seen as derivative of tetrahydrofuran (oxolane) with four methyl groups replacing four hydrogen atoms on each of the carbon atoms in the ring that are adjacent to the oxygen.
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