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A rapid strep test (also called rapid antigen detection testing or RADT) may also be used. While the rapid strep test is quicker, it has a lower sensitivity (70%) and statistically equal specificity (98%) as a throat culture. [13] In areas of the world where rheumatic fever is uncommon, a negative rapid strep test is sufficient to rule out the ...
Though strep throat can be treated with antibiotics, untreated infections can turn dangerous quickly. An iGAS infection can cause many different complications, some of which can be life-threatening.
No matter how you become infected, strep throat won't just go away on its own like viruses do. As a bacterial infection, it requires antibiotics. "Unless someone is allergic, penicillin is the ...
If the bacteria enters the bloodstream, the infection can become severe and life-threatening, and is called an invasive GAS (iGAS). [2] [3] Infection of GAS may spread through direct contact with mucus or sores on the skin. [2] GAS infections can cause over 500,000 deaths per year. [4]
An estimated 700 million GAS infections occur worldwide each year. While the overall mortality rate for these infections is less than 0.1%, over 650,000 of the cases are severe and invasive, and these cases have a mortality rate of 25%. [4] Early recognition and treatment are critical; diagnostic failure can result in sepsis and death.
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Rheumatic fever primarily affects children between ages 5 and 17 years and occurs approximately 20 days after strep throat. In up to a third of cases, the underlying strep infection may not have caused any symptoms. [citation needed] The rate of development of rheumatic fever in individuals with untreated strep infection is estimated to be 3%.
It may present as long red streaks spreading away from the site of infection. It is a possible medical emergency as involvement of the lymphatic system allows for an infection to spread rapidly. The most common cause of lymphangitis in humans is bacteria, in which case sepsis and death could result within hours if left untreated.
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