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A classic example of a syncytium is the formation of skeletal muscle.Large skeletal muscle fibers form by the fusion of thousands of individual muscle cells. The multinucleated arrangement is important in pathologic states such as myopathy, where focal necrosis (death) of a portion of a skeletal muscle fiber does not result in necrosis of the adjacent sections of that same skeletal muscle ...
A skeletal muscle cell is long and threadlike with many nuclei and is called a muscle fiber. [3] Muscle cells develop from embryonic precursor cells called myoblasts. [1] Skeletal muscle cells form by fusion of myoblasts to produce multinucleated cells in a process known as myogenesis.
Myogenesis is the formation of skeletal muscular tissue, particularly during embryonic development.. Myoblasts (cells with a single nucleus, represented in violet) fusing together to form muscle fibers (multinucleated muscle cells) during myogenesis
Skeletal muscle cells are the individual contractile cells within a muscle, and are often termed as muscle fibers. [3] A single muscle such as the biceps in a young adult male contains around 253,000 muscle fibers. [22] Skeletal muscle fibers are multinucleated with the nuclei often referred to as myonuclei.
Multinucleate cells (also known as multinucleated cells or polynuclear cells) are eukaryotic cells that have more than one nucleus, i.e., multiple nuclei share one common cytoplasm. Mitosis in multinucleate cells can occur either in a coordinated, synchronous manner where all nuclei divide simultaneously or asynchronously where individual ...
Skeletal muscle tissue consists of elongated, multinucleate muscle cells called muscle fibers, and is responsible for movements of the body. Other tissues in skeletal muscle include tendons and perimysium . [ 3 ]
These satellite cells are the main source of most muscle cell formation postnatally, with embryonic myoblasts being responsible for prenatal muscle generation. A single satellite cell can proliferate and become a larger amount of muscle cells. [28] With the understanding that myosatellite cells are the progenitor of most skeletal muscle cells ...
Cell fusion is an important cellular process in which several uninucleate cells (cells with a single nucleus) combine to form a multinucleate cell, known as a syncytium. Cell fusion occurs during differentiation of myoblasts , osteoclasts and trophoblasts , during embryogenesis , and morphogenesis . [ 1 ]