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  2. Benfotiamine - Wikipedia

    en.wikipedia.org/wiki/Benfotiamine

    Benfotiamine (rINN, or S-benzoylthiamine O-monophosphate) is a synthetic, fat-soluble, S-acyl derivative of thiamine (vitamin B1) that is approved in some countries as a medication or dietary supplement to treat diabetic sensorimotor polyneuropathy. Benfotiamine was developed in late 1950s in Japan.

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Some patients request to be switched to a different narcotic due to stigma associated with a particular drug (e.g. a patient refusing methadone due to its association with opioid addiction treatment). [4] Equianalgesic charts are also used when calculating an equivalent dosage of the same drug, but with a different route of administration.

  4. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose. [ 1 ] A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life .

  5. Maintenance dose - Wikipedia

    en.wikipedia.org/wiki/Maintenance_dose

    Continuing the maintenance dose for about 4 to 5 half-lives (t 1/2) of the drug will approximate the steady state level. [1] One or more doses higher than the maintenance dose can be given together at the beginning of therapy with a loading dose. [2] A loading dose is most useful for drugs that are eliminated from the body relatively slowly ...

  6. Dose (biochemistry) - Wikipedia

    en.wikipedia.org/wiki/Dose_(biochemistry)

    For example, if the desired total daily amount is 600 mg per day, they may decide a dosage plan that has one 200 mg dose taken three times a day, or one 300 mg dose taken twice a day, or a single 600 mg dose take once a day. Medication underdosing occurs commonly when physicians write prescriptions that are correct for a certain time, but fails ...

  7. Vitamin B1 analogues - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B1_analogues

    This article about an organic compound is a stub. You can help Wikipedia by expanding it.

  8. Talk:Benfotiamine - Wikipedia

    en.wikipedia.org/wiki/Talk:Benfotiamine

    As of October 2018, this study published in 2016 is still the most recent human study about taking oral Benfotiamine for a long time. 300mg/day benfotiamine given to Alzheimer patients for 18 months. No other doses were tested so it is impossible to know the optimal dose yet. Impressive benefits, but only 5 humans participated in the study!

  9. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    The AUC (from zero to infinity) represents the total drug exposure across time. AUC is a useful metric when trying to determine whether two formulations of the same dose (for example a capsule and a tablet) result in equal amounts of tissue or plasma exposure. Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic ...