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Many prescription and legal nonprescription substances can also cause withdrawal symptoms when individuals stop consuming them, even if they were taken as directed by a physician. The route of administration, whether intravenous , intramuscular , oral , or otherwise can also play a role in determining the severity of withdrawal symptoms.
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine . [ 4 ]
Medication discontinuation is the ceasing of a medication treatment for a patient by either the clinician or the patient themself. [1] [2] When initiated by the clinician, it is known as deprescribing. [3]
Methods of prevention include gradually decreasing the dose among those who wish to stop, though it is possible for symptoms to occur with tapering. [2] [6] [4] Treatment may include restarting the medication and slowly decreasing the dose. [2] People may also be switched to the long-acting antidepressant fluoxetine which can then be gradually ...
Sudden withdrawal from drugs such as alcohol, benzodiazepines, and barbiturates can be extremely dangerous, leading to potentially fatal seizures. For long-term alcoholics, going cold turkey can cause life-threatening delirium tremens. [1] In the case of opioid withdrawal, going "cold turkey" is extremely unpleasant but less dangerous.
A case study of two brothers with the condition, two years of treatment with hydrochlorothiazide reduced the incidence of kidney stones and improved kidney function. [22] The thiazide-like diuretic chlortalidone reduced urine calcium oxalate in seven of the eight males with inactivated CLCN5 gene that participated in the study. [ 23 ]
[2] [3] It decreases blood pressure mainly by hydrochlorothiazide while triamterene decreases the amount of potassium lost. [2] [3] The combination was approved for medical use in the United States in 1965. [5] In 2022, it was the 116th most commonly prescribed medication in the United States, with more than 5 million prescriptions. [6] [7]
Chlorothiazide, sold under the brand name Diuril among others, is an organic compound used as a diuretic and as an antihypertensive. [1] [2]It is used both within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure.