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Endoxifen, also known as 4-hydroxy-N-desmethyltamoxifen, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group as well as a protein kinase C (PKC) inhibitor. It is under development for the treatment of estrogen receptor -positive breast cancer and for the treatment of mania in bipolar disorder .
Phenylglycine is the organic compound with the formula C 6 H 5 CH(NH 2)CO 2 H. It is a non-proteinogenic alpha amino acid related to alanine, but with a phenyl group in place of the methyl group. It is a white solid. The compound exhibits some biological activity. [1]
Side effects of relugolix include menstrual abnormalities, hot flashes, excessive sweating, headache, and decreased bone mineral density. [ 7 ] [ 1 ] Relugolix is a GnRH antagonist, or an antagonist of the gonadotropin-releasing hormone receptor . [ 1 ]
"In some women, taking outside progesterone, or what we call 'exogenous progesterone,' either in the form of birth control or for other reasons, can sometimes cause your immune system to become ...
What the cramps feel like: Endometriosis often causes severe menstrual cramps that may begin before the period and last for days, says Melanie Bone, M.D., consultant ob/gyn and US medical director ...
The answer: period weight gain is normal, and it will start in the days before your period and go away once your period is over. People don't talk much about period weight gain, so you might be ...
Floxuridine is a pyrimidine analog that acts as an inhibitor of the S-phase of cell division. This selectively kills rapidly dividing cells. Antimetabolites masquerade as pyrimidine-like molecules which prevents normal pyrimidines from being incorporated into DNA during the S phase of the cell cycle.
The study included women admitted to hospital for one or more days for reasons other than delivery or venous thromboembolism. [5] Pregnancy after the age of 35 augments the risk of VTE, as does multigravidity of more than four pregnancies. [2] Pregnancy in itself causes approximately a five-fold increased risk of deep venous thrombosis. [6]