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  2. Trimethoprim/sulfamethoxazole - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim/sulfamethoxazole

    The effects of trimethoprim causes a backlog of dihydrofolate (DHF) and this backlog can work against the inhibitory effect the drug has on tetrahydrofolate biosynthesis. This is where the sulfamethoxazole comes in; its role is in depleting the excess DHF by preventing it from being synthesised in the first place. [14]

  3. Drug fever; Periarteritis nodosa; Hepatic necrosis; Pancreatitis; Myelosuppression; Haemolysis [a] Stevens–Johnson syndrome [b] Drug reaction with eosinophilia and systemic symptoms; Toxic epidermal necrolysis [c] Ataxia [d] Clostridioides difficile colitis; Aseptic meningitis [e] Pseudomembranous colitis; Interstitial nephritis; Fulminant ...

  4. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .

  5. Trimethoprim - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim

    Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea . [ 1 ] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS .

  6. Sulfamethoxazole - Wikipedia

    en.wikipedia.org/wiki/Sulfamethoxazole

    Sulfamethoxazole is primarily renally excreted via glomerular filtration and tubular secretion. [8] About 20% of the sulfamethoxazole in urine is the unchanged drug, about 15–20% is the N-glucuronide conjugate, and about 50–70 % is the acetylated metabolite. [11] Sulfamethoxazole is also excreted in human milk. [8]

  7. Folinic acid - Wikipedia

    en.wikipedia.org/wiki/Folinic_acid

    Sulfamethoxazole-trimethoprim: A potential drug interaction exists with concomitant use of sulfamethoxazole-trimethoprim and folinic acid. Folinic acid has been shown to decrease the efficacy of sulfamethoxazole-trimethoprim in the treatment of Pneumocystis jirovecii (formerly known as Pneumocystis carinii ), a common cause of pneumonia in AIDS ...

  8. 5 Ways Your Calcium Supplement May Interact with Medications ...

    www.aol.com/lifestyle/5-ways-calcium-supplement...

    But if you’re taking these medications, your supplement might backfire. Calcium supplements may be a bonus for bone health. But if you’re taking these medications, your supplement might ...

  9. Sulfonamide (medicine) - Wikipedia

    en.wikipedia.org/wiki/Sulfonamide_(medicine)

    Certain sulfonamides (sulfadiazine or sulfamethoxazole) are sometimes mixed with the drug trimethoprim, which acts against dihydrofolate reductase. As of 2013 [update] , the Republic of Ireland is the largest exporter worldwide of sulfonamides, accounting for approximately 32% of total exports.

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