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4-Phenylpiperidine is a chemical compound. It features a benzene ring bound to a piperidine ring. 4-Phenylpiperidine is the base structure for a variety of opioids , such as pethidine (meperidine), ketobemidone , alvimopan , loperamide , and diphenoxylate .
Chemical structure of 4-phenylpiperidine. Phenylpiperidines are chemical compounds with a phenyl moiety directly attached to piperidine. Of particular interest are a variety of derivatives of 4-phenylpiperidine, which have pharmacological effects including morphine-like activity [1] or other central nervous system effects.
Pyridine and poly(4-vinyl) pyridine have been shown to form conducting molecular wires with remarkable polyenimine structure on UV irradiation, a process which accounts for at least some of the visible light absorption by aged pyridine samples. These wires have been theoretically predicted to be both highly efficient electron donors and ...
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound. It is classified as a tetrahydropyridine . It is of interest as a precursor to the monoaminergic neurotoxin MPP + , which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain .
Bipyridines are a family of organic compounds with the formula (C 5 H 4 N) 2, consisting of two pyridyl (C 5 H 4 N) rings. Pyridine is an aromatic nitrogen-containing heterocycle. The bipyridines are all colourless solids, which are soluble in organic solvents and slightly soluble in water. Bipyridines, especially the 4,4' isomer, are mainly of ...
Picenadol (LY-97435) is a 4-phenyl piperidine derivative that is an opioid analgesic drug developed by Eli Lilly in the 1970s. [1] Picenadol is an effective analgesic with similar efficacy to pethidine (meperidine). It has been investigated for some applications such as obstetrics [2] and dentistry, [3] but never commercialised.
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes permanent symptoms of Parkinson's disease. (–)-Mitragynine is a naturally occurring tetrahydropyridine. 2,3,4,5-Tetrahydropyridine, a colorless liquid, is commercially available. It is an imine. Illustrating another isomer of tetrahydropyridine, 6-acetyl-2,3,4,5-tetrahydropyridine occurs ...
4-Benzylpiperidine is a drug and research chemical used in scientific studies. ... [4] Catalytic hydrogenation of the pyridine ring then completes the synthesis. [5]