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Streptomyces griseus, a bacterium once thought to be a fungus, was the commercial source of vitamin B 12 for many years. [132] The species Pseudomonas denitrificans and Propionibacterium freudenreichii subsp. shermanii are more commonly used today. [131] These are grown under special conditions to enhance yield.
What are the best food sources of B12? The most surefire way to get sufficient B12 from food is by eating animal-based products including, meat, poultry, seafood, eggs, and dairy. “Many animal ...
In a newly diagnosed vitamin B 12-deficient patient, normally defined as when serum levels are less than 200 pg/ml, daily IM injections of hydroxocobalamin up to 1,000 μg (1 mg) per day are given to replenish the body's depleted cobalamin stores. In the presence of neurological symptoms, following daily treatment, injections up to weekly or ...
Vitamin B 12 deficiency can be determined, but not always. [14] This means it measures forms of vitamin B 12 that are "active" and can be used by the body, as well as the "inactive" forms, which cannot. [150] Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2]
The elderly and athletes may need to supplement their intake of B 12 and other B vitamins due to problems in absorption and increased needs for energy production. [medical citation needed] In cases of severe deficiency, B vitamins, especially B 12, may also be delivered by injection to reverse deficiencies. [8] [unreliable medical source?
The structure of vitamin B 12 was the first low-molecular weight natural product determined by x-ray analysis rather than by chemical degradation. Thus, while the structure of this novel type of complex biomolecule was established, its chemistry remained essentially unknown; exploration of this chemistry became one of the tasks of the vitamin's chemical synthesis.
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