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A Jarisch–Herxheimer reaction is a sudden and typically transient reaction that may occur within 24 hours of being administered antibiotics for an infection by a spirochete, including syphilis, leptospirosis, Lyme disease, and relapsing fever. [1]
Serum sickness is a type III hypersensitivity reaction, caused by immune complexes. [2] When an antiserum is given, the human immune system can mistake the proteins present for harmful antigens . The body produces antibodies, which combine with these proteins to form immune complexes. [ 2 ]
Adolf Jarisch (February 15, 1850 – March 21, 1902) was an dermatologist from the Austro-Hungarian Empire who specialized in the care of venereal disease.The Jarisch-Herxheimer reaction, an inflammatory response that he noted following treatment for syphilis, is partially named after him.
Mycoplasma pneumonia is caused by a bacterium that can spread through droplets when an infected person coughs or sneezes. The bacterium can linger in the nose and throat without making a person ...
The Jarisch-Herxheimer reaction, which is the response to the body after endotoxins are released by the death of harmful organisms in the human body, starts usually during the first day of antibiotic treatment. [16]
The Jarisch–Herxheimer reaction is an immune-mediated response to syphilis therapy occurring within 2–24 hours. The exact mechanisms of reaction are unclear, however most likely caused by proinflammatory treponemal lipoproteins that are released from dead and dying organisms following antibiotic treatment.
Mycoplasma is a genus of bacteria that, like the other members of the class Mollicutes, lack a cell wall, and its peptidoglycan, around their cell membrane. [1] The absence of peptidoglycan makes them naturally resistant to antibiotics such as the beta-lactam antibiotics that target cell wall synthesis.
Karl Herxheimer (German pronunciation: [kaʁl ˈhɛʁksˌhaɪmɐ]; 26 June 1861 – 6 December 1942) was a German-Jewish dermatologist who was a native of Wiesbaden. He studied medicine at the universities of Freiburg , Strasbourg and Würzburg , receiving his doctorate in 1885 with a thesis on cerebral syphilis.