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Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). [5] Signs and symptoms may include blood in the stool , a change in bowel movements , weight loss, abdominal pain and fatigue. [ 9 ]
One study involving more than 1 million people with colon cancer from 2004 to 2015 found that 51.6% of those under 50 were diagnosed with stage three or four cancer, while 40% of people over 50 ...
Several risk factors for the development of colorectal cancer include high intake of fat, alcohol, red and processed meats, obesity, and lack of physical exercise. [46] A high-salt diet is linked to gastric cancer. Aflatoxin B1, a frequent food contaminate, is associated with liver cancer. Betel nut chewing has been shown to cause oral cancers ...
Colorectal cancer is a disease of old age. It typically originates in the secretory cells lining the gut, and risk factors include diets low in vegetable fibre and high in fat. If a younger person gets such a cancer, it is often associated with hereditary syndromes like Peutz-Jegher's, hereditary nonpolyposis colorectal cancer, or familial ...
Colorectal cancer risk and progression have both been linked to the microbiome, dysregulation of which has been linked to stress and disruption of the circadian rhythm.
The colorectal adenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal adenocarcinoma ( colon cancer ). [ 1 ] [ 2 ] [ 3 ] They often manifest as colorectal polyps .
For individual women, the discriminatory accuracy [5] for colon cancer was 0.67, for ovarian cancer 0.59, and for pancreatic cancer was 0.71. For individual men, the discriminatory accuracy [5] for colon cancer was 0.71 and for pancreatic cancer was 0.72. These values exceed the performance of many other cancer risk prediction tools. [6] [7]
Aside from colorectal cancer, the risk of others cancers is not increased in people with SPS. [14] Aspirin and nonsteroidal anti-inflammatory drug (NSAIDs) may be associated with a lower risk of SPS. [8] SPS is the most common polyposis syndrome affecting the colon. [5] There is no clear association of SPS with any cancers other than colorectal ...