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Schematic overview of the classes of stresses in plants Neurohormonal response to stress. Stress, whether physiological, biological or psychological, is an organism's response to a stressor such as an environmental condition. [1] When stressed by stimuli that alter an organism's environment, multiple systems respond across the body. [2]
Frequent stress: the magnitude and frequency of response to stress is what determines the level of allostatic load which affects the body. Failed shut-down: the inability of the body to shut off while stress accelerates and levels in the body exceed normal levels, for example, elevated blood pressure.
Once the stressor is resolved, the body resumes to amounting an adequate immune and inflammatory response, which may explain why it is often seen that a person falls ill after acute stress. Due to the interconnected nature of the brain's regulation of stress, the immune system, and the endocrine system, allostasis may play a role in the ...
Cell damage (also known as cell injury) is a variety of changes of stress that a cell suffers due to external as well as internal environmental changes. Amongst other causes, this can be due to physical, chemical, infectious, biological, nutritional or immunological factors. Cell damage can be reversible or irreversible.
Myonecrosis is the death of individual muscle fibres due to injury, hypoxia, or infection. Common causes include spontaneous diabetic myonecrosis (a.k.a. diabetic muscle infarction) and clostridial myonecrosis (a.k.a. gas gangrene). [11] Some spider bites may lead to necrosis.
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
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However, the problem arises when there is a persistent threat. First-time exposure to a stressor will trigger an acute stress response in the body; however, repeated and continuous exposure causes the stressor to become chronic. [4] McEwen and Stellar (1993) argued there is a "hidden cost of chronic stress to the body over long time periods". [8]