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The mean C max is higher in women than in men, 5.2 mg/L vs. 4.2 mg/L (p < 0.05), following a single 200 mg oral dose of modafinil. [108] This difference persists even after adjusting for body weight (0.88 ml/min/kg vs. 0.72 ml/min/kg). [108] The clearance of modafinil is 30% higher in men than in women, and plasma concentrations after a single ...
Upon analysis, scientists found that participants who stayed on standard statin treatment for their lifetime increased their quality-adjusted life years by 0.24-0.70, and those on higher-intensity ...
Masters athletics is a class of the sport of athletics for athletes of over 35 years of age. The events include track and field, road running and cross country running.These are the current world records in various five-year-groups, maintained by WMA, the World Association of Masters Athletes, which is designated by the World Athletics (formerly IAAF) to conduct the worldwide sport of Masters ...
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From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years. [ 119 ] and $13 billion a year at its peak, [ 120 ] Lipitor alone "provided up to a quarter of Pfizer Inc.'s annual revenue for years."
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
Estradiol valerate is usually used in the treatment of advanced prostate cancer in men at a dosage of 30 mg or more every 1 to 2 weeks by intramuscular injection. [13] In transgender women, estradiol valerate given by intramuscular injection is usually used at a dosage of 5 to 20 mg, but up to 30 to 40 mg, once every 2 weeks.