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  2. Zonisamide - Wikipedia

    en.wikipedia.org/wiki/Zonisamide

    Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...

  3. Levodopa - Wikipedia

    en.wikipedia.org/wiki/Levodopa

    Guggenheim tried levodopa at a dose of 2.5 mg and thought that it was inactive aside from nausea and vomiting. [ 3 ] In work that earned him a Nobel Prize in 2000, Swedish scientist Arvid Carlsson first showed in the 1950s that administering levodopa to animals with drug-induced ( reserpine ) Parkinsonian symptoms caused a reduction in the ...

  4. Droxidopa - Wikipedia

    en.wikipedia.org/wiki/Droxidopa

    Droxidopa, also known as (–)-threo-3-(3,4-dihydroxyphenyl)-L-serine (L-DOPS), is a substituted phenethylamine and is chemically analogous to levodopa (L-3,4-dihydroxyphenylalanine; L-DOPA). Whereas levodopa functions as a precursor and prodrug to dopamine, droxidopa is a precursor and prodrug of norepinephrine. [citation needed]

  5. DopAmide - Wikipedia

    en.wikipedia.org/wiki/DopAmide

    DopAmide, or L-DopAmide, is a synthetic levodopa (L-DOPA) analogue that can serve as a levodopa and dopamine prodrug and is of potential interest in the treatment of Parkinson's disease. [ 1 ] [ 2 ] [ 3 ] DopAmide has an amide rather than the carboxyl group of L -DOPA, [ 2 ] [ 3 ] which imparts greater water solubility .

  6. Management of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Parkinson's...

    Levodopa has also been related to a dopamine dysregulation syndrome, which is a compulsive overuse of the medication, and punding. [5] Controlled, slow-release versions of Sinemet and Madopar spread out the effect of the levodopa. Duodopa is a combination of levodopa and carbidopa. Slow-release levodopa preparations have not shown an increased ...

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    A pack of 32 Swiffer Dry refills might set you back nearly $10, which means you're spending around a quarter for every little touch-up — and much more if you go through multiple cloths or use ...

  8. What do turtles eat? Whether in the wild or your home, here's ...

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    In the United States, around 2.3 million households are home to reptiles, including turtles. Here's what the reptile can and cannot eat.

  9. Carbidopa/levodopa - Wikipedia

    en.wikipedia.org/wiki/Carbidopa/levodopa

    Carbidopa/levodopa, also known as levocarb and co-careldopa, is the combination of the two medications carbidopa and levodopa. [6] It is primarily used to manage the symptoms of Parkinson's disease, but it does not slow down the disease or stop it from getting worse. [6] It is taken by mouth. [6]

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