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Presentation depends on disease stage, location, and complications such as neurological deficits and abscesses. [5] Non-spinal symptoms include weakness, loss of appetite, weight loss, evening fever, and night sweats. [5] Clinical findings include back pain, paraparesis, kyphosis, sensory disturbances, and bowel and bladder dysfunction. [5]
Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a rare, adult-onset, X-linked recessive lower motor neuron disease caused by trinucleotide CAG repeat expansions in exon 1 of the androgen receptor (AR) gene, which results in both loss of AR function and toxic gain of function.
Symptoms for spinal tumors may vary due to factors such as the type of tumor, the region of the spine, and the health of the patient. Back pain is the most common symptom and it can be a problem if the pain is severe, has a time frame that lasts longer than it would for a normal injury, and becomes worse while laying down or at rest.
Women are more likely to exhibit symptoms [16] [17] They can also appear in clusters or bilaterally along the spine, thus symptoms can be unilateral, bilateral, or with symptoms more dominant on one side. The cases of reported symptomatic Tarlov cysts ranges from 15% to 30% of the overall reported Tarlov cyst case, depending on the source of ...
According to a 2008 study, the incidence of discitis in the United States is around 0.4 to 2.4 per 100,000 people each year depending on age group. [5] According to a later 2016 study, the combined prevalence of discitis and vertebral osteomyelitis with or without spinal epidural abscess for persons under 20 years old is uncommon (0.3 per 100,000 persons), and higher in older patients (6.5 per ...
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. [3] [4] [5] It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. [6]
Spinal cord injury; MRI of a fractured and dislocated cervical vertebra (C4) in the neck that is compressing the spinal cord: Specialty: Neurosurgery: Types: Complete, incomplete [1] Diagnostic method: Based on symptoms, medical imaging [1] Treatment: Spinal motion restriction, intravenous fluids, vasopressors [1] Frequency: c. 12,000 annually ...
Forward displacement of a proximal vertebra in relation to its adjacent vertebra in association with an intact neural arch, and in the presence of degenerative changes, is known as degenerative spondylolisthesis, [9] [10] which narrows the spinal canal, and symptoms of spinal stenosis are common. Of these, neural claudication is most common.