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The sale of mouse animal models began in 1933 with early sales to the United States Public Health Service and The Jackson Laboratory now provides a high proportion of the mice used in biomedical research [16] In particular, the C57BL/6J strain, which is widely used and cited is maintained at The Jackson Laboratory.
Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). [1]
The laboratory mouse has been instrumental in investigating the genetics of human disease, including cancer, for over 110 years. [1] The laboratory mouse has physiology and genetic characteristics very similar to humans providing powerful models for investigation of the genetic characteristics of disease.
The NSG mouse (NOD scid gamma mouse) is a brand of immunodeficient laboratory mice, developed and marketed by Jackson Laboratory, which carries the strain NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ. NSG branded mice are among the most immunodeficient described to date. [1] NSG branded mice lack mature T cells, B cells, and natural killer (NK) cells. [2]
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The data inside the ISO image will be structured according to the file system that was used on the optical disc from which it was created. ISO images can be created from optical discs by disk imaging software , or from a collection of files by optical disc authoring software , or from a different disk image file by means of conversion .
Name Description References deepBase: Identification, expression, evolution and function of long non-coding RNAs (LncRNAs), small RNAs and circular RNAs from deep-sequencing data [3] LNCipedia: A comprehensive compendium of human long non-coding RNAs. [4] [5] lncRNAdb: The Reference Database For Functional Long Noncoding RNAs. [6] LncRNAWiki