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U.S. Route 501 (US 501) is a spur of U.S. Route 1. It runs 355 miles (571 km) from Buena Vista, Virginia at U.S. Route 60 to Myrtle Beach, South Carolina at U.S. Route 17 Business. It passes through the states of Virginia, North Carolina and South Carolina. From Durham to Laurinburg, a 108-mile (174 km) section of US 501 overlaps U.S. Route 15.
U.S. Route 501 Business (US 501) is a 7.210-mile (11.603 km) business route of US 501 that exists in Marion. It is a former segment of US 501 [ citation needed ] that travels into downtown Marion. The highway begins south of Marion at a trumpet interchange , which also includes the beginning of a concurrency with South Carolina Highway 41 ...
US 76 / Wahee Road south to I-95 – Florence, Marion, Mullins: Western terminus of SC 576; northern terminus of Wahee Road; Robert J. McIntyre Sr. Intersection 3.090: 4.973: US 501 Bus. / SC 41 Alt. – Marion, Johnsonville, Conway, Myrtle Beach: Eastern terminus: 1.000 mi = 1.609 km; 1.000 km = 0.621 mi
Some of the region’s busiest roads, including U.S. 17, are in line for upgrades and realignments in the coming years.
Here, US 15 Business (US 15 Bus.)/US 501 Bus. split from US 15/US 501. Before the business routes rejoin on the other side of Durham, I-85 merges into US 15 Bus. Then, I-85/US 15 go north. Right after crossing Falls Lake at exit 186, US 15 splits off to the east. US 15 runs parallel to I-85, going through the city of Creedmoor.
US 501 Bus. north to US 701 north / SC 90 – Conway Business District, Conway Historic District, River Front: Western terminus: 0.260: 0.418: US 501 to US 378 – Myrtle Beach, Marion, Sumter: Access only from SC 544 westbound to US 501 northbound and SC 544 eastbound to US 501 southbound: 0.490: 0.789
US 15/US 501 turns left in Durham. From the South Carolina state line, US 15 is in concurrency with US 401 to Laurinburg.Merging with US 501, it becomes what is known as "15-501" ("Fifteen Five-o-one"), a concurrency that extends for 106 miles (171 km) across central North Carolina; US 15 also the dominant partner, using its milemarkers along the route.
US 301 / US 501 in Latta: SC 57 near Fork: 1939: 1942 SC 73 — — SR 73 at the Georgia state line southwest of Allendale: SC 5 / SC 641 in Sycamore: 1942: 1947 SC 73 — — US 17 Bus. in Springmaid Beach: US 17 Bus. in Myrtle Beach: 1960: 2006 SC 75: 8.110: 13.052 SC 5 / SC 75 Truck / Riverside Road in Van Wyck