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Definite neurosarcoidosis can only be diagnosed by plausible symptoms, a positive biopsy and no other possible explanations for the symptoms; Probable neurosarcoidosis can be diagnosed if the symptoms are suggestive, there is evidence of central nervous system inflammation (e.g. CSF and MRI), and other diagnoses have been excluded. A diagnosis ...
In 1995, Duffy was diagnosed with a rare form of the disease sarcoidosis called neurosarcoidosis. Her brain and spinal cord were affected, [10] leaving her partially paralyzed. Duffy is the author of the New York Times bestselling memoir Model Patient: My Life as an Incurable Wise-Ass.
Sarcoidosis affecting the nervous system is known as neurosarcoidosis. [54] Cranial nerves are most commonly affected, accounting for about 5–30% of neurosarcoidosis cases, and peripheral facial nerve palsy, often bilateral, is the most common neurological manifestation of sarcoidosis. [54] [55] [56] It occurs suddenly and is usually transient.
Löfgren syndrome is a type of acute sarcoidosis, [1] an inflammatory disorder characterized by swollen lymph nodes in the chest, tender red nodules on the shins, fever and arthritis. [2]
Sarcoidosis, an inflammatory disease, involves the skin in about 25% of patients.The most common lesions are erythema nodosum, plaques, maculopapular eruptions, subcutaneous nodules, and lupus pernio.
Neurosarcoidosis [27] Subacute sclerosing panencephalitis [28] Subarachnoid hemorrhage [29] Syphilis [30] Primary central nervous system lymphoma [31] Sjögren's syndrome [32] Guillain–Barré syndrome; Meningeal carcinomatosis [33] Multiple myeloma [34] Parry–Romberg syndrome
The condition was first described in 1909 by Danish ophthalmologist Christian Frederick Heerfordt, for whom the syndrome is now named. [6] It was originally attributed to mumps, but after further studies by Swedish doctor Jan G. Waldenström in 1937, it was classified as a distinct manifestation of sarcoidosis.
Facial nerve paralysis, sometimes bilateral, is a common manifestation of sarcoidosis of the nervous system, neurosarcoidosis. [6] Bilateral facial nerve paralysis may occur in Guillain–Barré syndrome, an autoimmune condition of the peripheral nervous system. [6]