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Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the virus SARS-CoV-1, the first identified strain of the SARS-related coronavirus. [3] The first known cases occurred in November 2002, and the syndrome caused the 2002–2004 SARS outbreak .
The major part of the outbreak lasted about 8 months, and the World Health Organization declared SARS contained on 5 July 2003. However, several SARS cases were reported until May 2004. [4] In late December 2019, SARS-CoV-2, a coronavirus in the same genus as the one that caused SARS, was discovered in Wuhan, Hubei, China.
Another common finding in SARS patients is a decrease in the number of lymphocytes circulating in the blood. [14] In the SARS outbreak of 2003, about 9% of patients with confirmed SARS-CoV-1 infection died. [15] The mortality rate was much higher for those over 60 years old, with mortality rates approaching 50% for this subset of patients. [15]
Another estimate suggests SARS-CoV-2 shares a common ancestor with bat coronavirus RmYN02 in about 1976. [172] SARS-CoV also possibly originated in around 1962 from the same horseshoe bats that harbours SARS-like coronaviruses. [116] It was transmitted humans in around 1998 (4.08 years prior to the outbreak in 2003). [173]
[21] [22] According to the World Health Organization, approximately 10 million new TB infections occur every year, and 1.5 million people die from it each year – making it the world's top infectious killer (before COVID-19 pandemic). [21] However, there is a lack of sources which describe major TB epidemics with definite time spans and death ...
On February 6, 57-year-old Patricia Dowd of San Jose, California became the first COVID-19 death in the United States (discovered by April 2020). She died at home without any known recent foreign travel, after being unusually sick from flu in late January, then recovering, working from home, and suddenly dying on February 6.
In 2003, following the outbreak of severe acute respiratory syndrome (SARS) which had begun the prior year in Asia, and secondary cases elsewhere in the world, the World Health Organization (WHO) issued a press release stating that a novel coronavirus identified by several laboratories was the causative agent for SARS. The virus was officially ...
Ebright has stated that the genome and properties of SARS-CoV-2 provide no basis to conclude the virus was engineered as a bioweapon, [28] [29] but he also has stated that the possibility that the virus entered humans through a laboratory accident cannot be dismissed and has called for a thorough investigation of the origin of the pandemic and for measures to reduce the risk of future pandemics.