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In the EPC trial, in which bicalutamide monotherapy (150 mg/day) was evaluated for treatment of early prostate cancer in 8,113 men, the incidence of abnormal liver function tests at 3-year median follow-up was 3.4% for bicalutamide plus standard care (n=4,052) and 1.9% for standard care alone (n=4,061).
Letrozole is the preferred treatment in those with infertility due to PCOS and is associated with a higher pregnancy rate than other treatments. [2] Both clomiphene and letrozole have a risk of a multiple gestation pregnancy, with the risk being less than 10%. [ 2 ]
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom and not the underlying cause of the disorder.
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However, an IUD causes the endometrial lining of a uterus to thin, which is the opposite of what occurs with PCOS. Levonorgestrel intrauterine devices (LNG-IUDs) have been associated with psychiatric symptoms, including depression, anxiety, and suicidal ideation, particularly in adolescents and young women, though evidence remains mixed.
Now, a new study has found yet another hardship associated with PCOS: cognitive decline in mid-life. Researchers followed 907 women for 30 years, according to the study published Jan. 31 in the ...
A single study suggests superiority of azithromycin over doxycycline. [34] Another alternative is to use a parenteral regimen with ceftriaxone or cefoxitin plus doxycycline. [ 27 ] Clinical experience guides decisions regarding transition from parenteral to oral therapy, which usually can be initiated within 24–48 hours of clinical improvement.
Zinc and vitamin D are also essential for bone health but have the added benefit for men over 50 by reducing the risk of erectile dysfunction, a condition commonly affecting men over age 40 ...
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