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  2. Myelodysplastic syndrome - Wikipedia

    en.wikipedia.org/wiki/Myelodysplastic_syndrome

    A myelodysplastic syndrome (MDS) is one of a group of cancers in which blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells. [3] Early on, no symptoms typically are seen. [3] Later, symptoms may include fatigue, shortness of breath, bleeding disorders, anemia, or frequent infections. [3]

  3. Howell-Jolly body-like inclusions - Wikipedia

    en.wikipedia.org/wiki/Howell-Jolly_body-like...

    They may appear in patients on immunosuppression and antiviral therapies with nucleoside analogs, anticancer chemotherapeutic agents, active COVID-19 infections, HIV/AIDS, and myelodysplastic syndrome. [3] [1]

  4. Chronic myelomonocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_myelomonocytic...

    [4] [10] [12] Decitabine/cedazuridine (Inqovi) is a fixed-dosed combination medication for the treatment of adults with myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) that was approved for use in the United States in July 2020. [27] Hematopoietic stem cell transplantation remains the only curative treatment for CMML ...

  5. Sideroblastic anemia - Wikipedia

    en.wikipedia.org/wiki/Sideroblastic_anemia

    Genetic syndromes: Rarely, sideroblastic anemia may be part of a congenital syndrome and present with associated findings, such as ataxia, myopathy, and pancreatic insufficiency. Acquired clonal sideroblastic anemia. Clonal sideroblastic anemias fall under the broader category of myelodysplastic syndromes (MDS).

  6. Howell–Jolly body - Wikipedia

    en.wikipedia.org/wiki/Howell–Jolly_body

    Howell–Jolly bodies are also seen in amyloidosis, severe hemolytic anemia, megaloblastic anemia, hereditary spherocytosis, and myelodysplastic syndrome (MDS). The bodies can also be seen in premature infants.

  7. Pappenheimer bodies - Wikipedia

    en.wikipedia.org/wiki/Pappenheimer_bodies

    A cell containing Pappenheimer bodies is a siderocyte. Reticulocytes often contain Pappenheimer bodies. They are mostly observed in diseases such as myelodysplastic syndrome (MDS), sideroblastic anemia, hemolytic anemia, lead poisoning and sickle cell disease. They can interfere with platelet counts when the analysis is performed by electro ...

  8. Dacrocyte - Wikipedia

    en.wikipedia.org/wiki/Dacrocyte

    A marked increase of dacrocytes is known as dacrocytosis. These tear drop cells are found primarily in diseases with bone marrow fibrosis, such as: primary myelofibrosis, myelodysplastic syndromes during the late course of the disease, rare form of acute leukemias and myelophthisis caused by metastatic cancers.

  9. Pelger–Huët anomaly - Wikipedia

    en.wikipedia.org/wiki/Pelger–Huët_anomaly

    Is a benign dominantly inherited defect of terminal neutrophil differentiation as a result of mutations in the lamin B receptor gene. The characteristic leukocyte appearance was first reported in 1928 by Karel Pelger (1885-1931), a Dutch Hematologist, who described leukocytes with dumbbell-shaped bilobed nuclei, a reduced number of nuclear segments, and coarse clumping of the nuclear chromatin.

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