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  2. Hepatic portal system - Wikipedia

    en.wikipedia.org/wiki/Hepatic_portal_system

    This mixture percolates through the sinusoids and collects in a central vein which drains into the hepatic vein. The hepatic vein subsequently drains into the inferior vena cava. The hepatic artery provides 30 to 40% of the oxygen to the liver, while only accounting for 25% of the total liver blood flow. The rest comes from the partially ...

  3. Portal vein - Wikipedia

    en.wikipedia.org/wiki/Portal_vein

    Approximately 75% of total liver blood flow is through the portal vein, with the remainder coming from the hepatic artery proper. The blood leaves the liver to the heart in the hepatic veins . The portal vein is not a true vein , because it conducts blood to capillary beds in the liver and not directly to the heart.

  4. Portal venous system - Wikipedia

    en.wikipedia.org/wiki/Portal_venous_system

    The human hepatic portal system delivers about three-fourths of the blood going to the liver.The final common pathway for transport of venous blood from spleen, pancreas, gallbladder and the abdominal portion of the gastrointestinal tract [2] (with the exception of the inferior part of the anal canal and sigmoid colon) is through the hepatic portal vein.

  5. Lobules of liver - Wikipedia

    en.wikipedia.org/wiki/Lobules_of_liver

    A portal triad (also known as portal canal, portal field [citation needed], portal area [citation needed], or portal tract [citation needed]) is a distinctive arrangement within lobules. It consists of the following five structures: [6] proper hepatic artery, an arteriole branch of the hepatic artery that supplies oxygen

  6. Transjugular intrahepatic portosystemic shunt - Wikipedia

    en.wikipedia.org/wiki/Transjugular_intrahepatic...

    By creating a shunt from the portal vein to the hepatic vein, this intervention allows portal blood an alternative avenue for draining into systemic circulation. In bypassing the flow-resistant liver, the net result is a reduced pressure drop across the liver and a decreased portal venous pressure. Decreased portal venous pressure in turn ...

  7. Porta hepatis - Wikipedia

    en.wikipedia.org/wiki/Porta_hepatis

    It transmits the following (in anterior to posterior order): common hepatic duct (leaving) proper hepatic artery (entering) hepatic portal vein (entering) The hepatic duct lies in front and to the right, the hepatic artery to the left, and the portal vein behind and between the duct and artery. It also transmits nerves and lymphatics.

  8. Portal hypertension - Wikipedia

    en.wikipedia.org/wiki/Portal_hypertension

    A dilated portal vein (diameter of greater than 13 or 15 mm) is a sign of portal hypertension, with a sensitivity estimated at 12.5% or 40%. [18] On Doppler ultrasonography, a slow velocity of <16 cm/s in addition to dilatation in the main portal vein are diagnostic of portal hypertension. [19]

  9. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    Illustration showing the hepatic portal vein system. The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.