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In May 2019, Tonix reported in-licensing the Phase 2 asset, TNX-1300 (T172R/G173Q double-mutant cocaine esterase 200 mg, i.v. solution), for the treatment of cocaine intoxication. [58] [59] TNX-1300 (formerly known as RBP-8000) is being developed under an Investigational New Drug application (IND) for the treatment of cocaine intoxication. [60]
Tianeptine/naloxone (developmental code names TNX-601, TNX-601-CR, TNX-601-ER), or naloxone/tianeptine, is an extended-release combination of tianeptine, an atypical μ-opioid receptor agonist, and naloxone, an orally inactive μ-opioid receptor antagonist, which was under development for the treatment of major depressive disorder, post-traumatic stress disorder (PTSD), and neurocognitive ...
As of Monday (the latest available data), 53% of 34 S&P 500 companies (comprising 10% of index earnings) that have reported so far beat on both sales and earnings per share, Bank of America’s ...
The market is entering the final two trading days of 2024, and stocks are set to post another strong year of gains. The Nasdaq Composite once again led the charge in 2024, rising more than 30% ...
Small-cap resurgence. Small caps were one of the beneficiaries of the post-Trump election rally. The Russell 2000 small-cap index jumped more than 5% on Wednesday for its best day in nearly two years.
The index was created in 1929 when all utility stocks were removed from the Dow Jones Industrial Average. On April 20, 1965, the index closed at 163.32. On September 13, 1974, the index closed at 57.93.
The CBOE Volatility Index, or VIX, jumped above 34, or well above its longer-run average of around 20. "The path of least resistance remains lower for global equity markets to start the week.
On July 17, 1995, the index closed above 1,000 for the first time. [8] Between 1995 and 2000, the peak of the dot-com bubble, the Nasdaq Composite stock market index rose 400%. It reached a price–earnings ratio of 200, dwarfing the peak price–earnings ratio of 80 for the Japanese Nikkei 225 during the Japanese asset price bubble of 1991. [9]
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