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The practice of intracardiac injection originated in the 1800s. It was commonly performed during the 1960s, as it was considered the fastest way to get medication to the heart. The practice began declining during the 1970s as more reliable delivery methods (i.e., intravenous , endotracheal , and intraosseous ) came into use.
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KCl is also sometimes used in fetal intracardiac injections in second- and third-trimester induced abortions. [ 16 ] [ 17 ] Jack Kevorkian 's thanatron machine injected a lethal dose of potassium chloride into the patient, which caused the heart to stop functioning, after a sodium thiopental -induced coma was achieved.
Catheters, electrodes, and other intracardiac prosthetic devices. Solid particles from repeated intravenous injections. Chronic inflammation. Examples include auto-immune mechanisms and degenerative valvular lesions. The risk factors for infective endocarditis provide a more extensive list of conditions that can damage the heart.