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Lung cancer is the leading cause of cancer death worldwide, with one in 16 people diagnosed with the disease in their lifetime. In the UK there are around 48,500 new cases every year, accounting ...
Osimertinib, sold under the brand name Tagrisso, [6] is a medication used to treat non-small-cell lung carcinomas with specific mutations. [7] [8] It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor.
Non-small cell lung cancer is a disease in which malignant cancer cells form in the tissues of the lung. [4] It is the most common type of lung cancer with up to 90% of all lung carcinomas falling into the non-small cell category. [4] Non-small cell lung cancer occurs when healthy cells become abnormal and grow rapidly. [4]
Cancer cells can also cause defects in the cellular pathways of apoptosis (programmed cell death). As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy drugs also cause DNA damage, which can be repaired by enzymes in the cell that carry out DNA ...
A once-daily pill from drugmaker AstraZeneca cut deaths in half among a subset of early-stage lung cancer patients who had undergone surgery, according to new clinical trial results.
Some cancer patients have tried several types of treatments, but their cancers may not have responded well. An oral pill in clinical trials shows promising results in lung cancer patients with ...
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