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Metabolic dysfunction–associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), [a] is a type of chronic liver disease.This condition is diagnosed when there is excessive fat build-up in the liver (hepatic steatosis), and at least one metabolic risk factor.
Resmetirom, sold under the brand name Rezdiffra, is a medication used for the treatment of noncirrhotic nonalcoholic steatohepatitis. [1] It is a thyroid hormone receptor beta (NR1A2) agonist. [1] The most common side effects include diarrhea and nausea. [2] Resmetirom was approved for medical use in the United States in March 2024.
Nonalcoholic steatohepatitis (NASH). ... so your best bet is to speak with a healthcare provider who can give you personalized advice on achieving your goals — and what those goals should look ...
In the study Children of the 90s, 2.5% born in 1991 and 1992 were found by ultrasound at the age of 18 to have non-alcoholic fatty liver disease; five years later transient elastography found over 20% to have the fatty deposits on the liver, indicating non-alcoholic fatty liver disease; half of those were classified as severe. The scans also ...
Alcoholic fatty liver disease is caused by drinking too much alcohol over an extended period of time. Risk Factors for Fatty Liver Disease Having overweight or obesity is a major risk factor for ...
Alcohol-associated (Alcohol-related) Liver Disease (ALD) Risk factors for MASLD include diabetes, obesity and metabolic syndrome. When inflammation is present it is referred to as alcoholic steatohepatitis and nonalcoholic (metabolic dysfunction associated) steatohepatitis (MASH, previously NASH). [2]
Belapectin (also known as GR-MD-02) is a galectin-3 inhibitor developed by Galectin Therapeutics that failed phase 3 clinical trials for the treatment of non-alcoholic steatohepatitis. [1] [2] [3] [4]
The drug is under development by Gilead as a treatment for non-alcoholic fatty liver disease. [3] References
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