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An ANA test is considered positive if fluorescence is seen at a titre of 1:40/1:80. Higher titres are more clinically significant as low positives (≤1:160) are found in up to 20% of healthy individuals, especially the elderly. Only around 5% of the healthy population have ANA titres of 1:160 or higher. [8] [53]
HEp-2 cells provide a greater ability to differentiate patterns of ANA than animal sections, due to the large nuclei and high mitotic rate of the cell line. Upon incubation with serum containing anti-dsDNA antibodies and fluorescent labelled secondary antibodies, homogeneous staining of interphase nuclei and condensed chromosomal staining of ...
A value of greater than 1.5 units relative to a control serum is considered a positive ELISA test for the anti-histone antibodies. Patients with drug-induced lupus erythematosus typically have positive tests for anti-histone antibodies but do not have indications for anti-dsDNA antibodies. Patients with idiopathic systemic lupus erythematosus ...
Mass concentration (g/dL or g/L) is the most common measurement unit in the United States. Is usually given with dL (decilitres) as the denominator in the United States, and usually with L (litres) in, for example, Sweden.
Homogeneity and heterogeneity; only ' b ' is homogeneous Homogeneity and heterogeneity are concepts relating to the uniformity of a substance, process or image.A homogeneous feature is uniform in composition or character (i.e., color, shape, size, weight, height, distribution, texture, language, income, disease, temperature, radioactivity, architectural design, etc.); one that is heterogeneous ...
The arithmetic mean, or less precisely the average, of a list of n numbers x 1, x 2, . . . , x n is the sum of the numbers divided by n: + + +. The geometric mean is similar, except that it is only defined for a list of nonnegative real numbers, and uses multiplication and a root in place of addition and division:
In statistics, homogeneity and its opposite, heterogeneity, arise in describing the properties of a dataset, or several datasets.They relate to the validity of the often convenient assumption that the statistical properties of any one part of an overall dataset are the same as any other part.
Of course, all matter is inhomogeneous at some scale, but frequently it is convenient to treat it as homogeneous. A good example is the continuum concept which is used in continuum mechanics . Under this assumption, materials such as fluids , solids , etc. can be treated as homogeneous materials and associated with these materials are material ...