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The commonly used epinephrine autoinjector delivers a 0.3 mg epinephrine injection (0.3 mL, 1:1000). [citation needed] It is indicated in the emergency treatment of allergic reactions, including anaphylaxis to stings, contrast agents, medicines, or people with a history of anaphylactic reactions to known triggers.
[1] [2] When anaphylaxis is suspected, epinephrine solution should be given as soon as possible as an intramuscular injection, in the middle of the outer side of the thigh, which corresponds to the location of the vastus lateralis muscle. [3] The injection may be repeated every 5 to 15 minutes if there is insufficient response. [4]
Racepinefrine (INN Tooltip International Nonproprietary Name, USAN Tooltip United States Adopted Name), or racepinephrine, sold under the brand name Vaponefrin among others, is a sympathomimetic medication described as a vasoconstrictor, bronchodilator, cardiostimulant, mydriatic, and antiglaucoma agent.
This is especially problematic with injectable medications given the extra work associated with an injection, as well as the potential aversion to self-injecting medication. [1] [2] Injector pens increase patient adherence by increasing the ease of self-administering injectable medication, as well as the portability of injection medication. [2]
β 1-Adrenergic receptor agonists, also known as beta-1 agonists, are a class of drugs that bind selectively to the β 1-adrenergic receptor. As a result, they act more selectively upon the heart . β-Adrenoceptors typically bind to norepinephrine release by sympathetic adrenergic nerves and to circulating epinephrine .
The closest method to IV/overall injection use, in terms of rapid onset, optimal bioavailability, and reduced health risks for most drugs, tends to be rectal administration via concentrated liquid solution (also known as a suppository), usually consisting of only ~1-3ml of liquid (typically not exceeding 5-10ml) assuming the drug in question ...
A depot injection, also known as a long-acting injectable (LAI), is a term for an injection formulation of a medication which releases slowly over time to permit less frequent administration of a medication.
An injection into the deltoid muscle is commonly administered using a 1-inch long needle, but may use a 5 ⁄ 8-inch long needle for younger people or very frail elderly people. [ 11 ] The ventrogluteal site on the hip is used for injections which require a larger volume to be administered, greater than 1 mL, and for medications which are known ...