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2. Antiestrogen - Wikipedia

   en.wikipedia.org/wiki/Antiestrogen

   Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inhibiting or suppressing estrogen production .

3. Exemestane - Wikipedia

   en.wikipedia.org/wiki/Exemestane

   Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women. The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by ...

4. List of side effects of estradiol - Wikipedia

   en.wikipedia.org/wiki/List_of_side_effects_of...

   List of side effects of estradiol which may occur as a result of its use or have been associated with estrogen and/or progestogen therapy includes: [1] [2]. Gynecological: changes in vaginal bleeding, dysmenorrhea, increase in size of uterine leiomyomata, vaginitis including vaginal candidiasis, changes in cervical secretion and cervical ectropion, ovarian cancer, endometrial hyperplasia ...

5. Anastrozole - Wikipedia

   en.wikipedia.org/wiki/Anastrozole

   Common side effects of anastrozole include hot flashes, altered mood, joint pain, and nausea. [7] [6] Severe side effects include an increased risk of heart disease and osteoporosis. [7] Use during pregnancy may harm the baby. [7] Anastrozole is in the aromatase-inhibiting family of medications. [7]

6. Selective estrogen receptor modulator - Wikipedia

   en.wikipedia.org/wiki/Selective_estrogen...

   Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), [1] [2] are a class of drugs that act on estrogen receptors (ERs). [3] Compared to pure ER agonists – antagonists (e.g., full agonists and silent antagonists ), SERMs are more tissue-specific, allowing them to selectively inhibit or ...

7. Steroidal aromatase inhibitor - Wikipedia

   en.wikipedia.org/wiki/Steroidal_aromatase_inhibitor

   Steroidal aromatase inhibitors are a class of drugs that are mostly used for treating breast cancer in postmenopausal women. High levels of estrogen in breast tissue increases the risk of developing breast cancer and the enzyme aromatase is considered to be a good therapeutic target when treating breast cancer due to it being involved in the final step of estrogen biosynthetic pathway and also ...

8. Estrogen (medication) - Wikipedia

   en.wikipedia.org/wiki/Estrogen_(medication)

   [84] [85] [86] The preceding side effects of synthetic estrogens do not appear to occur in pregnant women, who already have very high estrogen levels. [84] This suggests that these effects are due to estrogenic activity. [84] Synthetic estrogens have markedly stronger effects on the liver and hepatic protein synthesis than natural estrogens.

9. Tamoxifen - Wikipedia

   en.wikipedia.org/wiki/Tamoxifen

   The drug was subsequently reinvented from a failed contraceptive, to become tamoxifen, the gold standard for the adjuvant treatment of breast cancer and the pioneering medicine for chemprevention for high-risk women. [111] [112] Two books, Estrogen Action, Selective Estrogen Receptor Modulators and Women's Health (Imperial College Press 2013 ...