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The classic [13] [14] click reaction is the copper-catalyzed reaction of an azide with an alkyne to form a 5-membered heteroatom ring: a Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The first triazole synthesis, from diethyl acetylenedicarboxylate and phenyl azide, was reported by Arthur Michael in 1893. [ 15 ]
This isocyanide click reaction is a [4+1] cycloaddition followed by a retro-Diels Alder elimination of N 2. [12] The reaction proceeds with an initial [4+1] cycloaddition followed by a reversion to eliminate a thermodynamic sink and prevent reversibility. This product is stable if a tertiary amine or isocyanopropanoate is used.
Mental chronometry is the scientific study of processing speed or reaction time on cognitive tasks to infer the content, duration, and temporal sequencing of mental operations.
A Jensen box. The Odd-Man-Out Reaction Time test (OMO RT) is a test of reaction times that uses Arthur Jensen's testing apparatus, the Jensen box.The box is normally used for measuring choice reaction times in which the participant in the experiment is tested on their ability to recognize which of the eight lights of the Jensen box is illuminated, as quickly as possible. [1]
A psychomotor vigilance task (PVT) is a sustained-attention, reaction-timed task that measures the consistency with which subjects respond to a visual stimulus.Research indicates increased sleep debt or sleep deficit correlates with deteriorated alertness, slower problem solving, declined psychomotor skills, and increased rate of false responses.
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People who bought the recalled holiday candy are urged to call Gardners corporate office for a replacement at 1-800-242-2639, Monday through Friday from 7:30 a.m. to 4 p.m. Eastern time.