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The classic [13] [14] click reaction is the copper-catalyzed reaction of an azide with an alkyne to form a 5-membered heteroatom ring: a Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The first triazole synthesis, from diethyl acetylenedicarboxylate and phenyl azide, was reported by Arthur Michael in 1893. [ 15 ]
Mental chronometry is the scientific study of processing speed or reaction time on cognitive tasks to infer the content, duration, and temporal sequencing of mental operations.
Copper-free click chemistry is a bioorthogonal reaction as a variant of an azide-alkyne Huisgen cycloaddition. By eliminating cytotoxic copper catalysts, the reaction proceeds without live-cell toxicity. [ 1 ]
[2] [3] This reaction is accepted as a click chemistry reaction given the reactions' high yield, stereoselectivity, high rate, and thermodynamic driving force. Basic schematic of thiol-ene addition reaction. The reaction results in an anti-Markovnikov addition of a thiol compound to an alkene. Given the stereoselectivity, high rate and yields ...
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Simple reaction time correlates with general cognitive ability, [4] and there is some evidence that the slope of responding on the Jensen box does as well. [2] Ian Deary and colleagues, in a population-based cohort study of 900 individuals, demonstrated correlations between IQ and simple choice RTs between –0.3 and –0.5. [ 4 ]
A Jensen box. The Odd-Man-Out Reaction Time test (OMO RT) is a test of reaction times that uses Arthur Jensen's testing apparatus, the Jensen box.The box is normally used for measuring choice reaction times in which the participant in the experiment is tested on their ability to recognize which of the eight lights of the Jensen box is illuminated, as quickly as possible. [1]
The effect has been used to create a psychological test (the Stroop test) that is widely used in clinical practice and investigation. [ 1 ] A basic task that demonstrates this effect occurs when there is a mismatch between the name of a color (e.g., "blue", "green", or "red") and the color it is printed in (i.e., the word "red" printed in blue ...