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Viral load, also known as viral burden, is a numerical expression of the quantity of virus in a given volume of fluid, including biological and environmental specimens. It is not to be confused with viral titre or viral titer , which depends on the assay.
Human coronaviruses are capable of causing illnesses ranging from the common cold to more severe diseases such as Middle East respiratory syndrome (MERS, fatality rate ~34%). SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E , NL63 , OC43 , HKU1 , MERS-CoV , and the original SARS-CoV .
COVID-19 is more infectious than influenza, but less so than measles. [34] Estimates of the number of people infected by one person with COVID-19—the basic reproduction number (R 0)—have varied. In November 2020, a systematic review estimated R 0 of the original Wuhan strain to be approximately 2.87 (95% CI, 2.39 – 3.44). [90]
SARS-related coronavirus is a member of the genus Betacoronavirus (group 2) and monotypic of the subgenus Sarbecovirus (subgroup B). [13] Sarbecoviruses, unlike embecoviruses or alphacoronaviruses, have only one papain-like proteinase (PLpro) instead of two in the open reading frame ORF1ab. [14]
Scanning electron micrograph of SARS virions. Severe acute respiratory syndrome (SARS) is the disease caused by SARS-CoV-1. It causes an often severe illness and is marked initially by systemic symptoms of muscle pain, headache, and fever, followed in 2–14 days by the onset of respiratory symptoms, [13] mainly cough, dyspnea, and pneumonia.
Becoming seropositive for COVID-19 antibodies can occur due to either infection with COVID-19 itself or due to becoming vaccinated to COVID-19. [33] Being seropositive for COVID-19 does not intrinsically confer immunity or even resistance. However, higher rates of seroconversion are linked to greater clinical efficacy of vaccines.
Five pediatric deaths were reported during the week of Dec. 21, bringing the total number to nine so far during the 2024-25 season. The CDC says levels of the COVID-19 virus being detected in ...
The Delta variant (B.1.617.2) was [3] [4] a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in India on 5 October 2020. It was first detected in India on 5 October 2020. The Delta variant was named on 31 May 2021 and had spread to over 179 countries by 22 November 2021.