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Regarding creatine side effects. It's important to know what the true side effects are. People who use creatine may be taking other drugs or supplements that might be causing some of the side effects that are purported to be from creatine. For example, a high number of creatine users are bodybuilders who also take steroids.
Some studies have suggested that consumption of creatine with protein and carbohydrates can have a greater effect than creatine combined with either protein or carbohydrates alone. [ 27 ] While generally considered safe, long-term or excessive consumption of creatine may have an adverse effect on the kidneys , liver, or heart and should be ...
Creatine supplements are marketed in ethyl ester, gluconate, monohydrate, and nitrate forms. [40] Creatine supplementation for sporting performance enhancement is considered safe for short-term use but there is a lack of safety data for long term use, or for use in children and adolescents. [41] Some athletes choose to cycle on and off creatine ...
Pre-workout supplements contain a variety of ingredients such as caffeine and creatine, differing by capsule or powder products. [2] [3] The first pre-workout product entered the market in 1982, and since then the category has grown in use. [4] Some pre-workout products contain ingredients linked to adverse effects. [2]
Creatine is produced by the enzyme guanidinoacetate methyltransferase (GAMT). After production in the liver and kidneys, creatine is transported to organs and tissues with high energy demands, most commonly the brain and skeletal muscles. In addition to endogenous production, creatine can be obtained from dietary sources or supplementation.
Use of corticosteroids has numerous side-effects, some of which may be severe: Severe amoebic colitis : Fulminant amoebic colitis is associated with high case fatality and can occur in patients infected with the parasite Entamoeba histolytica after exposure to corticosteroid medications.
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