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A Mississippi River cruise offers the rare opportunity to sail through America's heartland on the world’s #1 river cruise line. Explore picturesque towns and boom cities; take in views of pastoral farms and towering bluffs; and immerse yourself in the region's rich history and culture with an included excursion in every port.
Find your next Mississippi river cruise with American Cruise Lines. Select from more than 12 unique itineraries on both modern riverboats and classic paddlewheelers.
Looking for the best Mississippi river cruises? Choose from Viking River Cruises, American Cruise Lines and American Queen Voyages to explore the highlights along the Mighty Mississippi.
Mississippi river cruises are a great way to explore the myriad top destinations along the fourth-longest river in the world: the Mississippi River. The Mississippi snakes its way from...
The ultimate Mississippi cruise - traversing the entire length of the river - stopping at all of the most iconic ports in the region, including New Orleans, Memphis, Hannibal, Winona, and more. prev.
Mississippi Explorer Cruise-American Symphony. Set sail on this brand-new itinerary to explore exclusive ports along the Mississippi River. Your adventure begins in the vibrant city of New Orleans and sails effortlessly to Memphis. In the comfort of our brand-new riverboat, enjoy a leisurely day of cruising as the shores of the Mississippi ...
Cruise America's great river on this 15-day itinerary aboard Viking Mississippi. Journey from St. Paul, Minnesota to New Orleans, Louisiana and explore highlights of the mighty Mississippi River. Along the way, visit historic ports such as St. Louis, Memphis, Baton Rouge, and more.
The 140-passenger vessel has ample indoor, and outdoor seating on all three decks, and wrap-around windows give way to amazing views. Our 2024 season offers 1-day, 2-day, and sightseeing cruises departing from LeClaire & Dubuque, Iowa. Where the river runs deep, so do the discoveries. BOOK NOW.
Below, see our favorite Mississippi River cruises to book in 2024, featuring stops in iconic American cities like Nashville, Memphis, and New Orleans.
We've rounded up the best Mississippi River cruises for seniors, history buffs and Americana lovers, so you can find your perfect U.S. river cruise itinerary based on your interests and travel preferences.