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Gigantism is usually caused by a tumor on the pituitary gland of the brain. It causes growth of the hands, face, and feet. It causes growth of the hands, face, and feet. [ 24 ] [ better source needed ] In some cases the condition can be passed on genetically through a mutated gene.
The pituitary gland or hypophysis is an endocrine gland in vertebrates. In humans, the pituitary gland is located at the base of the brain, protruding off the bottom of the hypothalamus. The human pituitary gland is oval shaped, about 1 cm in diameter, 0.5–1 gram (0.018–0.035 oz) in weight on average, and about the size of a kidney bean. [2 ...
Hyperpituitarism is a condition due to the primary hypersecretion of pituitary hormones; [3] [medical citation needed] it typically results from a pituitary adenoma.In children with hyperpituitarism, disruption of growth regulation is rare, either because of hormone hypersecretion or because of manifestations caused by local compression of the adenoma.
Julius Koch (1872 – 30 March 1902), also known as Le Géant Constantin ("Constantin the Giant"), was one of the tallest people ever. He suffered from gigantism, with an enlarged pituitary gland, testicular atrophy and lack of sexual development, [1] and had trouble walking. [2]
In people with GHRH-producing, non-pituitary tumors, the pituitary still may be enlarged and may be mistaken for a tumor. Therefore, it is important that physicians carefully analyze all "pituitary tumors" removed from people with acromegaly to not overlook the possibility that a tumor elsewhere in the body is causing the disorder. [citation ...
Pituitary gland dysfunction can occur from tumors, infections, surgeries, or for other reasons. When the pituitary gland doesn’t produce LH and FSH, there’s no signaling from the brain to the ...
Scientists extracted the hormone from the cadavers’ pituitary glands, located at the base of the brain. What the scientists didn’t realize at the time, however, was that in some cases, another ...
The presumed pathogenesis is that primary hypothyroidism causes enlargement and hyperstimulation of the pituitary gland which in turn cause ovarian hyperstimulation, ovarian cysts and precocious puberty. [citation needed]
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