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Treatment typically involves the use of topical eye drop steroids, intravitreal injection, newer biologics, and treating any underlying disease. While initial treatment is usually successful, complications include other ocular disorders, such as uveitic glaucoma , retinal detachment , optic nerve damage, cataracts , and in some cases, a ...
Patients are often asymptomatic and the disease is often discovered through investigation of the cause of the heterochromia or cataract. Neovascularisation (growth of new abnormal vessels) is possible and any eye surgery, such as cataract surgery, can cause bleeding from the fragile vessels in the atrophic iris causing accumulation of blood in ...
In addition to the blood vessels in the iris, they can grow into the angle of the eye. These blood vessels eventually go through a process called fibrosis which closes the normal physiologic anatomy of the angle. The closing of the angle prevents fluid from leaving the eye resulting in an increase in intraocular pressure.
Polycoria is a pathological condition of the eye characterized by more than one pupillary opening in the iris. [1] It may be congenital or result from a disease affecting the iris. [1] It results in decreased function of the iris and pupil, affecting the physical eye and visualization.
Many cases are asymptomatic, however patients many have decreased vision, glare, monocular diplopia or polyopia, and noticeable iris changes. [2] [5] On exam patients have normal to decreased visual acuity, and a "beaten metal appearance" of the corneal endothelium, corneal edema, increased intraocular pressure, peripheral anterior synechiae, and iris changes.
If there is an underlying cause, treatment should be given based on the disease. Non specific treatment measures include cycloplegics , corticosteroids and immunosuppressive drugs . [ 2 ] The biologic drugs that are currently used in treatment of panuveitis include anti tumor necrosis factor , cytokine receptor antibodies and interferon-α .
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Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye. It is a form of posterior uveitis. Inflammation of these layers can lead to vision-threatening complications. If only the choroid is inflamed, not the retina, the condition is termed choroiditis. [1]