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Other tumors such as adrenal tumors, pituitary gland tumors (such as a prolactinoma), or lung cancer, can produce hormones that alter the male–female hormone balance and cause gynecomastia. [22] Individuals with prostate cancer who are treated with androgen deprivation therapy may experience gynecomastia. [49]
Features of male breast cancers that differ from those in females include variations in their presentations, associations with other diseases, associations with non-medical predisposing conditions, expressions of key breast cancer-related hormones, causes (including frequency and forms of genetic alterations), tumor types, and treatments. [4]
Sometimes, gynecomastia and pseudogynecomastia are present together; this is related to the fact that fat tissue expresses aromatase, the enzyme responsible for the synthesis of estrogen, and estrogen is produced to a disproportionate extent in men with excessive amounts of fat, resulting in simultaneous glandular enlargement.
In 2023, 23,831 gynecomastia surgeries, reducing breast tissue for men, were performed in the U.S. Experts explain the rise in this procedure and the effect of increasing consciousness of body ...
"The most common sign of breast cancer is a lump, deep in the breast.It often feels hard, like a lemon seed, and usually immovable. It can be any shape or size," said the site. You might also see ...
A lump isn't the only sign of breast cancer to be aware of. These are the most uncommon breast cancer symptoms to know. ... There is a common myth that breast cancer doesn’t cause pain—but Dr ...
Galactorrhea can take place as a result of dysregulation of certain hormones. Hormonal causes most frequently associated with galactorrhea are hyperprolactinemia and thyroid conditions with elevated levels [a] of thyroid-stimulating hormone (TSH) or thyrotropin-releasing hormone (TRH). No obvious cause is found in about 50% of cases. [1]
A hormone-sensitive cancer, or hormone-dependent cancer, is a type of cancer that is dependent on a hormone for growth and/or survival. If a tumor is hormone-sensitive, it means that there are special proteins called receptors on cells surface. When the hormone bind the matched receptor, it results in growth and spread of cancer cells.