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  2. Fabry disease - Wikipedia

    en.wikipedia.org/wiki/Fabry_disease

    Fabry disease, also known as Anderson–Fabry disease, is a rare genetic disease that can affect many parts of the body, including the kidneys, heart, brain, and skin. [1] Fabry disease is one of a group of conditions known as lysosomal storage diseases .

  3. Sphingolipidoses - Wikipedia

    en.wikipedia.org/wiki/Sphingolipidoses

    Enzyme replacement therapy is available to treat mainly Fabry disease and Gaucher disease, and people with these types of sphingolipidoses may live well into adulthood. The other types are generally fatal by age 1 to 5 years for infantile forms, but progression may be mild for juvenile- or adult-onset forms.

  4. Farber disease - Wikipedia

    en.wikipedia.org/wiki/Farber_disease

    Farber disease (also known as Farber's lipogranulomatosis, acid ceramidase deficiency, "Lipogranulomatosis", [2] and ASAH1-related disorders) is an extremely rare, progressive, autosomal recessive lysosomal storage disease caused by a deficiency of the acid ceramidase enzyme.

  5. Lysosomal storage disease - Wikipedia

    en.wikipedia.org/wiki/Lysosomal_storage_disease

    Lysosomal storage diseases (LSDs; / ˌ l aɪ s ə ˈ s oʊ m əl /) are a group of over 70 rare inherited metabolic disorders that result from defects in lysosomal function. [1] [2] Lysosomes are sacs of enzymes within cells that digest large molecules and pass the fragments on to other parts of the cell for recycling.

  6. Lipid storage disorder - Wikipedia

    en.wikipedia.org/wiki/Lipid_storage_disorder

    They are generally inherited in an autosomal recessive fashion, but Fabry disease is X-linked. Taken together, sphingolipidoses have an incidence of approximately 1 in 10,000. Enzyme replacement therapy is available mainly to treat Fabry disease and Gaucher disease and people with these types of sphingolipidoses may live well into adulthood ...

  7. 4D Molecular Shares Updated Data From Fabry Disease Trial

    www.aol.com/news/4d-molecular-shares-updated...

    4D Molecular Therapeutics Inc (NASDAQ: FDMT) has posted updated interim data from the Phase 1/2 trial of 4D-310 in Fabry disease at the 18th Annual WORLDSymposium. Following 4D-310 infusion, mean ...

  8. GLA (gene) - Wikipedia

    en.wikipedia.org/wiki/GLA_(gene)

    This disease may have late onset and only affect the heart or kidneys. [8] Fabry disease is an X-linked disease, affecting 1 in 40,000 males. However, unlike other X-linked diseases, this condition also creates significant medical problems for females carrying only 1 copy of the defective GLA gene.

  9. ‘Today’ Fans Beg Al Roker to ‘Take Care’ of Himself After New ...

    www.aol.com/lifestyle/today-fans-beg-al-roker...

    'Today' show star Al Roker got honest about aging, and fans are saying he needs to "take care of himself" after seeing his Instagram.