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Ionis Pharmaceuticals, Inc. is a biotechnology company based in Carlsbad, California, that specializes in discovering and developing RNA-targeted therapeutics.The company has three commercially approved medicines: Spinraza (), Tegsedi (), and Waylivra (Volanesorsen), and has four drugs in pivotal studies: tominersen for Huntington's disease (together with Roche), tofersen for SOD1-ALS, AKCEA ...
The company developed data center and network architecture to enable internet access, becoming one of the first web hosting companies. [3] Ten years later, in 1998, 1&1 became a shareholder of Schlund+Partner. [4] In 2000, the company changed its name to United Internet and moved its product business to 1&1 Internet AG. In the same year, 1&1 ...
Legacy systems are considered to be potentially problematic by some software engineers for several reasons. [4]If legacy software runs on only antiquated hardware, the cost of maintaining the system may eventually outweigh the cost of replacing both the software and hardware unless some form of emulation or backward compatibility allows the software to run on new hardware.
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Ionis' application for the drug was based on data from a late-stage study in which it helped reduce triglyceride levels by 44% in patients, compared to a placebo.
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