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Losartan, sold under the brand name Cozaar among others, is a medication used to treat high blood pressure (hypertension). [4] It is in the angiotensin receptor blocker (ARB) family of medication, and is considered protective of the kidneys.
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. [2] A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor . [ 3 ]
This mechanism involves the direct effects of antipsychotic drugs on glutamate receptors. By using the technique of functional neurochemical assay chlorpromazine and phenothiazine derivatives have been shown to have inhibitory effects on NMDA receptors that appeared to be mediated by action at the Zn site. It was found that there is an increase ...
DOGE wants access to filers’ data, and the commerce secretary says Trump wants to scrap the IRS. But filing a return remains mandatory — the earlier the better, tax advisers say.
Walmart's Presidents' Day sales are here. Save on Dyson vacuums, Apple AirPods, sheet sets, mattresses, and more.
The United States will leave the World Health Organization on Jan. 22, 2026, the United Nations said on Thursday, after being formally notified of the decision by President Donald Trump, who has ...
Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient.
Fifteen years ago, Leslie Knope, a character on the hit TV series "Parks and Recreation," introduced a new way of celebrating love: Galentine’s Day.