Search results
Results from the WOW.Com Content Network
Sir John Bertrand Gurdon FRS (born 2 October 1933) is a British developmental biologist, best known for his pioneering research in nuclear transplantation [2] [3] [4] and cloning. [ 1 ] [ 5 ] [ 6 ] [ 7 ]
John Gurdon clones an animal, a frog tadpole, from an egg cell using the nucleus from an intestinal cell (1962). Roger W. Sperry shows the potential independence of the two sides of the human brain using split-brain patients (1962–1965). Nirenberg and Leder experiment, binding tRNA to ribosomes with synthetic RNA to decipher the genetic code ...
In particular, the research of Sir John Gurdon in 1958 entailed the cloning of Xenopus laevis utilizing the principles of SCNT. [5] In short, the experiment consisted of inducing a female specimen to ovulate, at which point her eggs were harvested. From here, the egg was enucleated using ultra-violet irradiation to disable the egg's pronucleus.
In 1958, John Gurdon, then at Oxford University, explained that he had successfully cloned a frog. He did this by using intact nuclei from somatic cells from a Xenopus tadpole. [40] This was an important extension of work of Briggs and King in 1952 on transplanting nuclei from embryonic blastula cells.
Dolly Dolly (taxidermy) Other name(s) 6LLS (code name) Species Domestic sheep (Finn-Dorset) Sex Female Born (1996-07-05) 5 July 1996 Roslin Institute, Midlothian, Scotland Died 14 February 2003 (2003-02-14) (aged 6) Roslin Institute, Midlothian, Scotland Cause of death Euthanasia Resting place National Museum of Scotland (remains on display) Nation from United Kingdom (Scotland) Known for ...
The first vertebrate ever to be cloned was an African clawed frog in 1962, [35] an experiment for which Sir John Gurdon was awarded the Nobel Prize in Physiology or Medicine in 2012 "for the discovery that mature cells can be reprogrammed to become pluripotent". [36]
Specifically, John Gurdon's experiments showed that a mature or differentiated cell nucleus can be returned to its immature undifferentiated form; this is the first instance of cloning of a vertebrate animal. Experiment: Gurdon used a technique known as nuclear transfer to replace the killed-off nucleus of a frog (Xenopus) egg with a nucleus ...
1958 – John Gurdon used nuclear transplantation to clone an African Clawed Frog; first cloning of a vertebrate using a nucleus from a fully differentiated adult cell. 1958 – Matthew Stanley Meselson and Franklin W. Stahl proved that DNA replication is semiconservative in the Meselson-Stahl experiment