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N-acetylphosphatidylethanolamine-hydrolysing phospholipase D (EC 3.1.4.54, NAPE-PLD, anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, NAPE-hydrolyzing phospholipase D) is an enzyme with systematic name N-acetylphosphatidylethanolamine phosphatidohydrolase. [1] [2] It catalyses the following chemical reaction
N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) is an enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE). This is a major part of the process that converts ordinary lipids into chemical signals like anandamide and oleoylethanolamine .
A hydrophobic cavity in NAPE-PLD provides an entryway for the substrate NAPE into the active site, where a binuclear zinc center orchestrates its hydrolysis. Unexpectedly, the structure unveils bile acids bind the membrane enzyme, enhancing dimer assembly and enabling catalysis.
NAPE-PLD may refer to: N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [ wikidata ] N-acyl phosphatidylethanolamine-specific phospholipase D , an enzyme
A client portal is an electronic gateway to a collection of digital files, services, and information, accessible over the Internet through a web browser. The term is most often applied to a sharing mechanism between an organization and its clients . [ 1 ]
Schedule 2 (S2) drugs and poisons, otherwise known as Pharmacy Medicines, are substances and preparations for therapeutic use that – are substantially safe in use but where advice or counselling is available if necessary; are for minor ailments or symptoms that – can be easily recognised by the consumer and
A common method is to direct all World Wide Web traffic to a web server, which returns an HTTP redirect to a captive portal. [8] When a modern, Internet-enabled device first connects to a network, it sends out an HTTP request to a detection URL predefined by its vendor and expects an HTTP status code 200 OK or 204 No Content.
Napa State Hospital is a psychiatric hospital in Napa, California, founded in 1875. It is located along California State Route 221, the Napa-Vallejo Highway, and is one of California's five state mental hospitals. Napa State Hospital holds civil and forensic mental patients in a sprawling 138-acre campus. According to a hospital spokesperson ...