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Shingles, also known as herpes zoster or zona, [6] is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [7] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1]
Shingles vaccination is the only way for adults to be protected against both shingles and postherpetic neuralgia, with two vaccines approved for use in people over age 50. [3] The zoster vaccine Shingrix provides around 90% protection from postherpetic neuralgia, and has been used in many countries since 2017.
Mayo Clinic is a nonprofit hospital system with campuses in Rochester, Minnesota; Scottsdale and Phoenix, Arizona; and Jacksonville, Florida. [22] [23] Mayo Clinic employs 76,000 people, including more than 7,300 physicians and clinical residents and over 66,000 allied health staff, as of 2022. [5]
The painful infection is very common and often starts with a tingling feeling in the skin
A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which is also responsible for chickenpox. [ 8 ] Shingles provokes a painful rash with blisters, and can be followed by chronic pain ( postherpetic neuralgia ), as well as other complications.
The recent study also found that having had shingles carried a higher risk of subjective cognitive decline for men who carried the gene APOE4 — associated with cognitive impairment and dementia ...
Lymphedema, which causes swelling on the arms and/or legs, can also put an individual at risk. [ citation needed ] Diseases that affect blood circulation in the legs and feet, such as chronic venous insufficiency and varicose veins , are also risk factors for cellulitis.
Aciclovir risks causing resistance to antiviral agents, and in 1% to 10% of cases can cause unpleasant side effects. [19] Aciclovir taken by mouth does not appear to decrease the risk of pain after shingles. [20] In those with herpes of the eye, aciclovir may be more effective and safer than idoxuridine. [21]