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At 48 weeks, for example, retatrutide had reduced levels of triglycerides by up to 40.6%, and levels of a protein called apoC-III involved in glucose metabolism and inflammation by 38%.
New weight loss drug retatrutide shows promise in trial, doctors say. Chloe Nordquist. July 13, 2023 at 2:08 PM. A closeup of a beam scale is seen in New York on April 3, 2018.
Retatrutide (LY-3437943) is an experimental drug for obesity developed by American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist ( GLP-1 , GIP , and GCGR receptors). [ 1 ]
Eli Lilly's retatrutide has been called the "King Kong" of weight loss shots: in early trials, people on the highest dose of this medication lost an average of 24% of their body weight in one year.
GLP1 poly-agonist peptides [1] are a class of drugs that activate multiple peptide hormone receptors including the glucagon-like peptide-1 (GLP-1) receptor.These drugs are developed for the same indications as GLP-1 receptor agonists—especially obesity, type 2 diabetes, and non-alcoholic fatty liver disease.
Tirzepatide [12] is an antidiabetic medication used to treat type 2 diabetes [9] [13] [14] [15] and for weight loss. [10] [16] Tirzepatide is administered via subcutaneous injections (under the skin).
Eli Lily’s weight-loss drug retatrutide helped patients lose 24% of their body weight, new data shows. The results rivaled Ozempic. Experts share what to know.
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