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The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature.
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
It is in pregnancy category X, meaning that it is known to result in negative outcomes for the fetus if taken during pregnancy. [11] In rare cases, uterine rupture may occur. [11] It is a prostaglandin analogue—specifically, a synthetic prostaglandin E 1 (PGE 1). [11] Misoprostol was developed in 1973. [20]
Ergonovine is listed as Table I precursors under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, as possible precursor compound for LSD. [29] As an N -alkyl derivative of ergine, ergonovine is also covered by the Misuse of Drugs Act 1971 , effectively rendering it illegal in the United Kingdom .
Bicalutamide is pregnancy category X, or "contraindicated in pregnancy", in the U.S., [27] and pregnancy category D, the second most restricted rating, in Australia. [89] As such, it is contraindicated in women during pregnancy, and women who are sexually active and who can or may become pregnant are strongly recommended to take bicalutamide ...
A medical abortion, also known as medication abortion or non-surgical abortion, occurs when drugs are used to bring about an abortion. Medical abortions are an alternative to surgical abortions such as vacuum aspiration or dilation and curettage. [6] Medical abortions are more common than surgical abortions in most places around the world.
In response to decreased tetrahydrofolate (THF), the cell begins to transcribe more DHF reductase, the enzyme that reduces DHF to THF. Because methotrexate is a competitive inhibitor of DHF reductase, increased concentrations of DHF reductase can overcome the drugs inhibition. Many new drugs are under development to reduce antifolate drug ...
Topiramate was approved for medical use in the United States in 1996. [9] It is available as a generic medication . [ 10 ] [ 15 ] [ 16 ] In 2022, it was the 84th most commonly prescribed medication in the United States, with more than 8 million prescriptions.